2026 Update

Reviewed by Dr. Scott Maymon

Reading time: three minutes

Hormone balance plays an essential role in men’s overall health. When testosterone, thyroid hormones, and adrenal hormones function smoothly, men experience consistent energy, stable mood, strong metabolism, and healthy sexual function. When those systems fall out of balance, the effects are often gradual and they can significantly impact quality of life.

Common Hormonal Imbalances in Men

Hormonal changes affect men differently at each stage of life. While aging plays a role, younger men today also experience imbalances due to chronic stress, poor sleep, environmental toxins, and metabolic issues.

Low Testosterone (Andropause)

Testosterone naturally declines with age, but a more significant drop can lead to symptoms such as:

  • Low energy
  • Reduced libido
  • Erectile dysfunction
  • Decreased muscle mass
  • Mood changes
  • Weight gain

Because testosterone influences so many systems in the body, even mild deficiencies can create ripple effects.

Thyroid Dysfunction

Both underactive and overactive thyroid function can contribute to:

  • Fatigue
  • Weight fluctuations
  • Temperature intolerance
  • Difficulty concentrating
  • Changes in heart rate

Thyroid hormones work closely with testosterone and cortisol, so balance across all systems is important.

Adrenal Dysregulation

Chronic stress affects cortisol production, often resulting in:

  • Persistent fatigue
  • Sleep disruption
  • Increased irritability
  • Sugar and salt cravings
  • Abdominal weight gain

Over time, cortisol imbalance can contribute to testosterone suppression and metabolic issues.

How Hormonal Imbalances Affect Men’s Health

Hormones regulate sleep, metabolism, sexual function, cognition, and mood. When these levels shift, men may notice:

  • Physical changes: Reduced muscle strength, slower metabolism, decreased stamina, and shifts in body fat.
  • Cognitive changes: Difficulty concentrating, reduced motivation, forgetfulness, or brain fog.
  • Emotional changes: Irritability, mood swings, increased stress sensitivity, or low mood.

Long-Term Risks

Untreated hormonal imbalance may contribute to cardiovascular issues, insulin resistance, metabolic disorders, and decreased bone density.

Recognizing these changes early is key to preventing more significant health concerns.

Treatment Options for Hormonal Imbalance in Men

At Pure Body Health, hormone evaluation includes a detailed symptom review, comprehensive lab testing, and a full assessment of metabolic and adrenal function. Our approach to hormone health helps identify the underlying factors contributing to low testosterone and related symptoms.

Testosterone Replacement Therapy (TRT)

TRT is the primary medical treatment for clinically low testosterone. It restores testosterone into a healthy range to address various symptoms such as fatigue, low libido, erectile dysfunction, mood changes, and loss of strength.

Testosterone replacement therapy can help:

  • Improve energy levels
  • Support muscle development and metabolism
  • Enhance mood and mental clarity
  • Restore libido and sexual function
  • Support long-term metabolic and cardiovascular health

TRT is generally administered by injection or sublingual troches. 

Additional Support for Hormone Health

Addressing testosterone alone is not always enough. Many men benefit from supporting related systems that influence hormone production and metabolism.

Lifestyle and functional health support may include:

  • Strength training and activity guidance
  • Sleep optimization
  • Nutrient and metabolic assessment
  • Stress regulation and adrenal support
  • Nutrition adjustments for blood sugar stability

These factors help the body respond more effectively to TRT and support long-term health.

Take Charge of Your Hormonal Health

Whether you are experiencing fatigue, mood changes, reduced libido, or unexplained weight gain, hormone testing can offer valuable insight. 

To book an appointment at our wellness clinic in Tempe, call (480) 427-0442 or complete the online inquiry form. Visit us at 1553 W Todd Drive, Suite 106, Tempe, AZ.

FAQs

What is TRT?

Testosterone Replacement Therapy restores testosterone levels when the body is no longer producing enough on its own. It helps improve energy, mood, strength, libido, and metabolic health.

How do I know if I have low testosterone?

Low testosterone does not look the same for everyone. Some men experience physical changes, while others notice differences in mood, concentration, or sexual health. Testing provides clarity and helps your provider identify the root cause.

How soon will I notice results with TRT?

Many men feel improvements in energy and sleep within a few weeks. Physical changes such as increased muscle strength or reduced fat mass may take several months.

Is TRT safe?

TRT is generally safe when monitored by a trained provider. Regular lab work ensures testosterone stays within a healthy range and helps track red blood cell counts, prostate markers, and metabolic changes.

Can lifestyle changes improve testosterone naturally?

Testosterone naturally declines by about 1% per year after age 30. Lifestyle improvements such as quality sleep, resistance training, stress management, and balanced nutrition can support how your body uses testosterone and may ease some symptoms. However, if your levels are already low, these changes alone rarely raise testosterone into a healthy range. Supplementation through medically supervised TRT is the most reliable way to increase low levels.

Where can I get testosterone replacement therapy near me?

Men in Tempe and the surrounding East Valley can receive personalized testosterone replacement therapy at Pure Body Health. Our providers offer comprehensive hormone testing and customized TRT plans designed to support energy, strength, and long-term wellness.

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