Reviewed by Dr. Scott Maymon, ND, NPH

Reading time: three minutes

If you have ever been told your anxiety is “just stress” or “in your head,” you are not alone, and you are not wrong to wonder if something deeper is going on. 

Many women are diagnosed with an anxiety disorder and prescribed medication without anyone ever checking their hormone levels. But science is catching up to what many women have long suspected: hormonal imbalances can play a major role in anxiety, and they are often overlooked in mainstream mental health care.

At Pure Body Health, we believe women deserve a more complete picture of what is driving their symptoms. 

In this blog, we will explore the connection between hormones and anxiety, how different stages of the menstrual cycle impact mood, and why treating hormonal anxiety requires more than just addressing the brain.

Can Hormone Imbalance Cause Anxiety?

Hormonal fluctuations can absolutely affect anxiety levels! Hormones act as chemical messengers in the body, influencing everything from heart rate and digestion to mood regulation and sexual function. 

When levels of key steroid hormones such as estrogen, progesterone, thyroid hormones, and cortisol shift out of balance, it can lead to a wide range of anxiety symptoms.

These imbalances do not just cause irritability or fatigue. They can also trigger feelings of anxiety, racing thoughts, insomnia, panic attacks, and even social withdrawal. These are all symptoms that are often misclassified as generalized anxiety disorder or social anxiety disorder when the root cause is hormonal.

Hormones and Anxiety Throughout the Menstrual Cycle

Women are uniquely affected by the menstrual cycle, which involves natural but significant changes in hormone levels every month. Understanding these changes is key to recognizing hormone-related anxiety.

Follicular Phase (Day 1–14)

During the first half of the cycle, estrogen levels gradually rise. This phase is generally associated with more stable moods and energy levels. However, low thyroid hormones or poor blood sugar regulation can still lead to symptoms of hormonal anxiety, even in this more balanced window.

Luteal Phase (Day 15–28)

After ovulation, progesterone rises and estrogen drops. For many women, this shift can lead to increased anxiety symptoms, including mood swings, restlessness, and panic-like episodes. 

These changes may be part of premenstrual syndrome (PMS) or more severe forms such as premenstrual dysphoric disorder (PMDD).

If anxiety symptoms consistently increase in the second half of the cycle, hormones may be contributing to the pattern.

How Cortisol and Chronic Stress Complicate Things

Cortisol, the body’s primary stress hormone, plays a critical role in anxiety. When an individual is under significant stress, cortisol levels stay elevated, putting strain on both physical health and mental health.

High cortisol can disrupt the balance of other hormones, worsen mood disorders, interfere with sexual function, and intensify symptoms of anxiety. Over time, this creates a cycle in which unresolved stress contributes to persistent hormone imbalances, which in turn increase anxiety levels.

Why Women Are Often Misdiagnosed

The differences in anxiety disorders between men and women are rarely addressed in conventional care. 

Many providers do not routinely assess hormone levels when a woman presents with anxiety symptoms, even when those symptoms clearly align with the menstrual cycle or life stages such as perimenopause or postpartum.

Instead, women are often prescribed anti-anxiety medications or antidepressants without consideration for hormone-related anxiety as a potential root cause. This approach may overlook an important driver of symptoms and lead to incomplete or temporary relief.

What You Can Do About Hormonal Anxiety

At Pure Body Health, we offer diagnostic testing and individualized treatment plans to help identify and address the underlying causes of hormone-related symptoms.

Our services may include:

  • Comprehensive hormone panels to evaluate estrogen, progesterone,  DHEA, thyroid hormones, and cortisol.
  • Functional medicine support for menstrual cycle regulation and perimenopausal transitions.
  • Nutrition-based strategies to support a balanced diet and hormone stability.
  • Bioidentical hormone replacement therapy when appropriate.
  • Ongoing monitoring to evaluate hormone levels and treatment response.

Each plan is based on objective data and tailored to the individual, with the goal of improving both mental and physical well-being.

Learn more about Women’s Hormone Optimization Therapy

Book a Consultation in Tempe, AZ

Persistent anxiety symptoms, especially when they follow cyclical patterns or coincide with hormonal changes, may indicate an endocrine cause. Evaluation and treatment of hormonal factors can provide a more complete path to relief.

We provide an evidence-based approach to hormonal anxiety, combining lab testing, clinical insight, and personalized care. 

To book an appointment at our wellness clinic in Tempe, call (480) 427-0442 or complete the online inquiry form. Visit us at 1553 W Todd Drive, Suite 106, Tempe, AZ.